Defzil 6

Each uncoated tablet contains :

Deflazacort 6 mg

Defzil 30

Each uncoated tablet contains :

Deflazacort 30 mg

About the drug: Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant. Deflazacort is a prodrug. Its potency is around 70–90% that of prednisolone. Prednisolone is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant drug. It is used to treat certain inflammatory diseases and (at higher doses) some types of cancer, but has significant adverse effects as it suppresses the immune system, it leaves patients more susceptible to infections.

Prednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity. Alpha GR and Beta GR are found in virtually all tissues with variable numbers between 3000 and 10000 per cell, depending on the tissue involved. Prednisolone can activate and influence biochemical behaviour of most cells & can suppress the regulation of genes.

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